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Welcome to the Portal for the Research Group of Professor Michael Holdsworth

by Michael Holdsworth last modified 12-12-2014 09:09




The University web page of Professor Michael Holdsworth is here.
How do plants survive in a hostile world? Plants cannot run away when confronted with a problem, they have to sit it out and try to survive. This means that they have evolved to respond in specific ways to different environmental changes, which provides an adaptive advantage to those that do it best.

Current areas of interest include:
  • Characterisation of the plant N-end rule pathway of targeted proteolysis.
  • Understanding the role of targeted proteolysis in sensing plant-environment interactions.
  • Gasotransmitters and gas sensing.
  • Providing molecular resources and conceptual frameworks that plant breeders and growers can use.

  • Research papers highlighting these areas:
    Sophie, Jorge and Guille presenting at Science@suttonbonington2014

    photo

    Contact us:
    Division of Plant & Crop Sciences
    University of Nottingham
    Sutton Bonington Campus
    Loughborough Leics
    LE12 5RD, UK

    Detailed instructions for reaching the campus are available.

    People:

    Michael
Holdsworth


    Researchers:

  • Dr Guillermina Mendiondo, Barry Axcell Fellow
  • Dr Cristina Mariana Sousa Correia
  • Dr Jorge Vicente Conde
  • Dr Tinne Boeckx
  • Sophie Berckhan, PhD student
  • Geeta Prasad, PhD student
  • Daniel Rooney, PhD student
  • Julietta Marquez
  • GUS seedling

    The role of the N-end rule pathway of targeted proteolysis in the control of plant growth and development.

    Gibbs et al. Molecular Cell (2014): Discovery of a general mechanism of nitric oxide sensing in plants.
    Gibbs et al. Nature (2011): Discovery of the mechanism of oxygen sensing in plants.
    Holman et al. PNAS (2009): First discovery of a developmental function for the N-end rule pathway in plants.


    SeedNet

    Systems approaches to understanding the control of seed germination and seedling establishment.

    Bassel et al. PNAS (USA) (2014) 4D modelling of a germinating Arabidopsis embryo.

    Bassel et al. PNAS (USA) (2011) Genome wide network analysis of seed dormancy and germination.


    PHS

    Transfer of molecular genetic information from studies in model species, to address important agricultural problems associated with plant developmental biology and response to abiotic stress.

    Mendiondo et al. J. Ex. Bot. (2014) The function of COMATOSE in barley.

    Gerjets et al. J. Ex. Bot. (2010) Definition of the key physiological processes leading to Pre-Harvest Sprouting in wheat.



    Work in the laboratory is funded by:


    BBSRCSABMiller


    Community Resources


    The Virtual Seed Web Resource vseed.nottingham.ac.uk:
    This online resource provides queryable interfaces for Gene Networks associated with seed development, dormancy and germination. Users can zoom into networks, search and highlight genes of interest and download images of network representations.



    TAGGIT analysis of seed transcriptome datasets: (original reference: Carrera et al. Plant Physiology 2007): TAGGIT uses a seed germination/dormancy ontology to annotate 'omics datasets, thus allowing more biologically informed analysis. A guide and most up-to-date version (although not updated since 2009, you can also use your own gene lists) of the TAGGIT workflow.





    Thanks to the University of Nottingham MyCIB (Multidisciplinary Centre for Integrative Biology), especially Tom Gallagher, John Veasey and Alex Marshall for help setting up this portal.
    Site managed by Professor Michael Holdsworth, University of Nottingham.

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    Last update 12 Dec 2014.


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